research August 1, 2026 via Health Technol Assess

Interventions to reduce pain at dressing change of chronic wounds: a mixed-methods systematic review.

This systematic review examined interventions to reduce pain during dressing changes for chronic wounds, including diabetic foot ulcers. Pain during dressing changes is a significant issue that can cause stress and fear, potentially hindering wound healing. The researchers analyzed 29 studies, encompassing clinical trials, surveys, and interviews with patients and healthcare providers. They found that pain levels vary widely depending on wound type and healing stage. Some non-adhesive dressings and certain topical sprays or gels appeared to reduce pain, but results were inconsistent, and no single method worked for everyone. Importantly, the way healthcare professionals communicate with and prepare patients before dressing changes also influenced pain perception. Effective pain management is crucial for improving patient comfort and quality of life, and may support better healing outcomes. However, due to the heterogeneity of the studies, definitive recommendations are challenging, and further research is needed to establish best practices.

Medically reviewed by Professor Cheng Wang, MD

Key takeaways

  • Pain during dressing changes is common for chronic wounds like diabetic foot ulcers, causing distress and fear.
  • This review of 29 studies found that pain varies by wound type and healing stage, and no single method always works.
  • Non-adhesive dressings and topical sprays or gels may reduce pain, but results were mixed across studies.
  • Good communication and preparing patients before dressing changes can help lower anxiety and perceived pain.
  • Ask your doctor whether non-adhesive dressings or pain-relief sprays might be suitable for your wound.
  • Always tell your healthcare team if dressing changes are painful, so they can adjust your care plan.

Editor's note

In China, diabetic foot ulcer care is becoming more specialized, with dedicated centers focusing on wound management and pain control. This review supports what many Chinese clinicians are already doing, such as using advanced dressings and taking time to talk with patients. While some specific products mentioned may not be available everywhere, the principle of reducing pain during dressing changes is widely accepted. Patients in China should feel empowered to discuss pain management with their doctors and ask about options like non-adhesive dressings or topical anesthetics if available.

This content summarizes published medical research for educational purposes only. It does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making treatment decisions.

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